ADENOCARCINOMA IN-SITU OF THE UTERINE CENIX PROGRESSING TO INVASIVE ADENOCARCINOMA

This report documents a case of adenocarcinoma in situ (AIS) of the ce rvix progressing to invasive adenocarcinoma. The patient, who was 32-y ears-old at the time of diagnosis of AIS, was followed with negative s mears for 7 years after conization when a smear showed malignant gland ular cells, A repeat conization demonstrated well differentiated papil lary adenocarcinoma. The patient remains well 8 years after radical hy sterectomy and lymph node dissection. The clinicopathological features of this case and a brief review of the literature are presented.