DIPUUPEHEDIONE, A CYTOTOXIC NEW RED DIMER FROM A NEW CALEDONIAN MARINE SPONGE HYRTIOS SP

Authors
BOURGUETKONDRACKI ML DEBITUS C GUYOT M
Citation
Ml. Bourguetkondracki et al., DIPUUPEHEDIONE, A CYTOTOXIC NEW RED DIMER FROM A NEW CALEDONIAN MARINE SPONGE HYRTIOS SP, Tetrahedron letters, 37(22), 1996, pp. 3861-3864
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
22
Year of publication
1996
Pages
3861 - 3864
Database
ISI
SICI code
0040-4039(1996)37:22<3861:DACNRD>2.0.ZU;2-K
Abstract
Dipuupehedione, a cytotoxic new red dimer of puupehenone was isolated from a New Caledonian marine sponge Hyrtios sp. and its structure esta blished through spectral studies, including extensive 2 D NMR spectros copy. Dipuupehedione is active on KB cells (IC50 = 3 mu g/ml). Copyrig ht (C) 1996 Published by Elsevier Science Ltd