NOVEL 1,2-BRIDGED CALIX[4]CROWNS IN THE 1,2-ALTERNATE CONFORMATION

Authors
PAPPALARDO S PETRINGA A PARISI MF FERGUSON G
Citation
S. Pappalardo et al., NOVEL 1,2-BRIDGED CALIX[4]CROWNS IN THE 1,2-ALTERNATE CONFORMATION, Tetrahedron letters, 37(22), 1996, pp. 3907-3910
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
22
Year of publication
1996
Pages
3907 - 3910
Database
ISI
SICI code
0040-4039(1996)37:22<3907:N1CIT1>2.0.ZU;2-N
Abstract
Treatment of 1,2-di[(2-pyridylmethyl)oxy]calix[4] arenes 1(R = t-Bu, I I) with tri- to pentaethylene glycol ditosylates in anhydrous toluene in the presence of t-BuOK affords a mixture of 1,2-alternate and cone (I,2)-calix[4]crown conformers 2 and 3 in a 55-70% overall yield. The conformational features of 2 have been deduced by NMR and further conf irmed by single-crystal X-ray analysis on crown-5 derivative 2e. Copyr ight (C) 1996 Elsevier Science Ltd