A SHORT DIPOLAR CYCLOADDITION APPROACH TO GAMMA-LACTAM ALKALOIDS FROMCYNOMETRA-HANKEI

Authors
FISHWICK CWG FOSTER RJ CARR RE
Citation
Cwg. Fishwick et al., A SHORT DIPOLAR CYCLOADDITION APPROACH TO GAMMA-LACTAM ALKALOIDS FROMCYNOMETRA-HANKEI, Tetrahedron letters, 37(22), 1996, pp. 3915-3918
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
22
Year of publication
1996
Pages
3915 - 3918
Database
ISI
SICI code
0040-4039(1996)37:22<3915:ASDCAT>2.0.ZU;2-H
Abstract
The gamma-lactam based alkaloid cynometrine has been synthesised in fo ur steps from 1-methyl-imidazole-4-carboxaldehyde. The key step involv es an efficient regio-, stereo-, and chemoselective 1,3-dipolar cycloa ddition of a dithiolane-fused azomethine ylide. Copyright (C) 1996 Els evier Science Ltd