J. Abadie et al., REGULATION OF DIETARY-FAT PREFERENCE - ESTABLISHING A REPRODUCIBLE PROFILE OF DIETARY-FAT PREFERENCE IN RATS, Life sciences, 53(2), 1993, pp. 131-139
The mechanism(s) underlying preference for individual macronutrients (
particularly fat) in diet are poorly understood. The greatest obstacle
in designing experiments to define neurochemical determinants of fat
preference lies in our ability to clearly identify animals, macronutri
ent preference (MP) profile. To this end, we have defined the role of
several variables and suggested ways to design better studies to exami
ne the mechanism of macronutrient preference. The results of these stu
dies show that the paradigm used for MP analysis, genetics and age of
the animal could clearly affect the MP profile.