Due to its rarity, cervical thymic cyst is seldom included in the diff
erential diagnosis of a neck mass. Approximately 80 cases have been re
ported thus far, and most of these cases have occurred asymptomaticall
y in children and adults. Only 5 cases have involved patients younger
than 1 year of age. The authors report four new patients with thymic c
yst in the neck. Two of the patients were newborns in whom the cyst ca
used airway obstruction and dysphagia. All four patients underwent suc
cessful resection of the lesions, with complete resolution of symptoms
. The embryology, histopathology, and differential diagnosis of cervic
al thymic cysts are also reviewed. The authors recommend that despite
its infrequent occurrence, cervical thymic cyst should be considered i
n the evaluation of neck masses in children.