To determine trends in a number of hemodialysis associated diseases an
d practices, the Centers for Disease Control and Prevention, in collab
oration with the Health Care Financing Administration, performed a mai
l survey of 2,304 chronic hemodialysis centers in the United States in
1993. By the end of 1993, at least three doses of hepatitis B vaccine
were administered to 29% of patients and 76% of staff at responding c
enters. Hepatitis B surface antigen was present at low frequency in pa
tients (incidence = 0.1%, prevalence 1.2%) and staff members (incidenc
e = 0.02%, prevalence = 0.3%). The 1993 incidence of hepatitis B virus
infection among patients was higher at centers that accepted hepatiti
s B surface antigen positive patients but did not use a separate room
and dialysis machine for treatment of these patients, government and p
rofit (versus nonprofit) centers, and centers in four End Stage Renal
Disease Networks. The prevalence of antibody to hepatitis C virus was
9.7% among patients and 1.6% among staff members. Pyrogenic reactions
in the absence of septicemia were reported by 21% of centers and assoc
iated with use of high flux dialysis. Human immunodeficiency virus inf
ection was known to be present in 1.5% of patients; 34% of centers rep
orted providing hemodialysis to one or more human immunodeficiency vir
us infected patients.