SYNTHESIS, BIOLOGICAL-ACTIVITY AND QUANTITATIVE STRUCTURE-ACTIVITY-RELATIONSHIPS OF N-SUBSTITUTED-3,4-DIHYDRO-2H-1-BENZOPYRAN DERIVATIVES

Authors
MAROT C COMOY C VIAUD MC RETTORI MC PFEIFFER B MORINALLORY L GUILLAUMET G
Citation
C. Marot et al., SYNTHESIS, BIOLOGICAL-ACTIVITY AND QUANTITATIVE STRUCTURE-ACTIVITY-RELATIONSHIPS OF N-SUBSTITUTED-3,4-DIHYDRO-2H-1-BENZOPYRAN DERIVATIVES, Bioorganic & medicinal chemistry letters, 6(10), 1996, pp. 1077-1082
Citations number
20
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
6
Issue
10
Year of publication
1996
Pages
1077 - 1082
Database
ISI
SICI code
0960-894X(1996)6:10<1077:SBAQS>2.0.ZU;2-H
Abstract
Synthesis of N-substituted-3,4-dihydro-2H-1-benzopyran derivatives whi ch have a potential affinity for the 5-HT1A receptor is reported. The comparison between the experimental values of binding and the predicti on of Q.S.A.R. studies is described. (C) 1996 Elsevier Science Ltd