RADIATION-ASSOCIATED GLIOSARCOMA

The authors report a case of radiation-associated intracerebral gliosa rcoma with fibrosarcomatous predominance, arising at the site of a low -grade glioma treated 10 years previously. The features of this case c onform to the accepted criteria for radiation-induced tumour, in that the tumour developed within the radiation field, differed dramatically in histologic features from the original tumour and did not develop u ntil 10 years after treatment. Although such tumours are most uncommon , this case suggests that radiation-induced gliosarcoma should be cons idered in the differential diagnosis of recurrent mass at the site of a treated intracranial neoplasm.