CHARACTERIZATION OF A PLASMODIUM-FALCIPARUM MEROZOITE SURFACE-ANTIGENTARGETED BY DEFENSE-MECHANISMS DEVELOPED IN IMMUNE INDIVIDUALS

Authors
OEUVRAY C BOUHAROUNTAYOUN H FILGUEIRA MC GRASMASSE H TARTAR A DRUILHE P
Citation
C. Oeuvray et al., CHARACTERIZATION OF A PLASMODIUM-FALCIPARUM MEROZOITE SURFACE-ANTIGENTARGETED BY DEFENSE-MECHANISMS DEVELOPED IN IMMUNE INDIVIDUALS, Comptes rendus de l'Academie des sciences. Serie 3, Sciences de la vie, 316(4), 1993, pp. 395-399
Citations number
14
Categorie Soggetti
Multidisciplinary Sciences
Journal title
Comptes rendus de l'Academie des sciences. Serie 3, Sciences de la vie → ACNP
ISSN journal
07644469
Volume
316
Issue
4
Year of publication
1993
Pages
395 - 399
Database
ISI
SICI code
0764-4469(1993)316:4<395:COAPMS>2.0.ZU;2-S
Abstract
We report the identification of a 48 kDa antigen targetted by antibodi es which inhibit P. falciparum in vitro growth by cooperation with blo od monocytes in an ADCl assay correlated to the naturally acquired pro tection. This protein is located on the surface of the merozoite stage , and is detectable in all isolates tested.