The extract from steamed sweet potato was found to suppress the melano
genesis of mouse melanoma B 16 cells. The compounds showing the suppre
ssion of the melanogenesis in the extract of sweet potato were separat
ed by Toyopearl(R) HW 40 C column chromatography and HPLC. Steamed swe
et potato contained chlorogenic acid and three kinds of isochlorogenic
acids as the main phenolic constituents. These four phenolic compound
s suppressed the melanogenesis equally. The melanogenesis suppressing
ratio of the phenolics corresponded to 98% of total suppressing activi
ty of the extract from steamed sweet potato.