Radiation hazard during previous manned space flights was not a critic
al problem as seen from monitoring on board MIR and the SHUTTLE. Futur
e Martian and Lunar missions as well as flights on inclined or high al
titude orbits around the Earth can be exposed to a large radiobiologic
al risk and critical reliability losses can be expected, due to Single
Event Effects on VLSI devices. The mains characteristics of these haz
ards and some counter-measures to be provided for are given.