R. Tambini et al., POSSIBLE PATHOGENIC ROLE FOR SPOROTHRIX CYANESCENS ISOLATED FROM A LUNG LESION IN A HEART-TRANSPLANT PATIENT, Journal of medical and veterinary mycology, 34(3), 1996, pp. 195-198
Sporothrix cyanescens is a fungus rarely isolated from human specimens
. Its pathogenic role has never been demonstrated but has been postula
ted on the basis of its occurrence in normally sterile body sites, its
isolation from debilitated individuals and its thermotolerance. A fir
st case of nodular pulmonary lesions developing in an immunosuppressed
, heart transplant patient is reported. Sporothrix cyanescens was isol
ated from a fine needle lung biopsy. The patient failed to respond to
itraconazole therapy, whereas he was successfully treated with amphote
ricin B.