AMPHOTERICIN-B RESISTANT ISOLATES OF CRYPTOCOCCUS-NEOFORMANS WITHOUT ALTERATION IN STEROL BIOSYNTHESIS

Authors
JOSEPHHORNE T LOEFFLER RST HOLLOMON DW KELLY SL
Citation
T. Josephhorne et al., AMPHOTERICIN-B RESISTANT ISOLATES OF CRYPTOCOCCUS-NEOFORMANS WITHOUT ALTERATION IN STEROL BIOSYNTHESIS, Journal of medical and veterinary mycology, 34(3), 1996, pp. 223-225
Citations number
13
Categorie Soggetti
Mycology
Journal title
Journal of medical and veterinary mycology → ACNP
ISSN journal
02681218
Volume
34
Issue
3
Year of publication
1996
Pages
223 - 225
Database
ISI
SICI code
0268-1218(1996)34:3<223:ARIOCW>2.0.ZU;2-C
Abstract
Amphotericin B resistant mutants of Cryptococcus neoformans were isola ted accumulating mainly ergosterol. Cross-resistance to azole antifung als was not observed. Together with previous data this indicates that at least three categories of amphotericin B resistance can arise: ster ol mutants, amphotericin B and azole cross-resistant mutants and ampho tericin B resistant mutants with no azole cross-resistance.