CHIRAL POLYHYDROXYLATED TETRAHYDROTHIOPHENE DERIVATIVES - NOVEL SYNTHESIS AND STRUCTURAL ELUCIDATION BY X-RAY CRYSTALLOGRAPHY, NMR-SPECTROSCOPY AND MOLECULAR MECHANICS CALCULATIONS

Authors
RAO AVR REDDY KA SRINIVAS NR GURJAR MK PADMAJA N RAMAKUMAR S VISWAMITRA MA SWAPNA GVT JAGANNADH B KUNWAR AC
Citation
Avr. Rao et al., CHIRAL POLYHYDROXYLATED TETRAHYDROTHIOPHENE DERIVATIVES - NOVEL SYNTHESIS AND STRUCTURAL ELUCIDATION BY X-RAY CRYSTALLOGRAPHY, NMR-SPECTROSCOPY AND MOLECULAR MECHANICS CALCULATIONS, Journal of the Chemical Society. Perkin transactions. I, (11), 1993, pp. 1255-1259
Citations number
24
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of the Chemical Society. Perkin transactions. I → ACNP
ISSN journal
0300922X
Issue
11
Year of publication
1993
Pages
1255 - 1259
Database
ISI
SICI code
0300-922X(1993):11<1255:CPTD-N>2.0.ZU;2-L
Abstract
The dideoxygenation reaction of -alkylidene-2,5-di-S-methylthiocarbony l-D-mannitol derivatives under Barton-McCombie reaction conditions gav e the hexahydrodipyranothiophenes 4 and 7 instead of the expected 2,5- dideoxy products. Structural and conformational information on these n ovel derivatives has been obtained by NMR spectroscopy, single-crystal X-ray crystallography and molecular mechanics calculations.