RAT HEPATOCYTES IN SINGLE-CELL SUSPENSION - A STILL SUITABLE SYSTEM FOR LIPID-PEROXIDATION STUDIES

Authors
POLI G BIASI F CHIARPOTTO E SCAVAZZA A
Citation
G. Poli et al., RAT HEPATOCYTES IN SINGLE-CELL SUSPENSION - A STILL SUITABLE SYSTEM FOR LIPID-PEROXIDATION STUDIES, Cytotechnology, 11, 1993, pp. 9-11
Citations number
6
Categorie Soggetti
Biothechnology & Applied Migrobiology
Journal title
Cytotechnology → ACNP
ISSN journal
09209069
Volume
11
Year of publication
1993
Supplement
1
Pages
9 - 11
Database
ISI
SICI code
0920-9069(1993)11:<9:RHISS->2.0.ZU;2-7
Abstract
The investigation of toxic compounds which need a previous metabolic a ctivation often gets advantage by the employment of cell suspensions, in most of the cases rat hepatocytes. In particular, this model system allows the characterization of lipid peroxidation kinetics, the evalu ation of its pathogenetic role in the induction of cell death and the analysis of the interaction among different prooxidant compounds in br inging about both oxidative damage and cytolysis.