ISOLATION AND IDENTIFICATION OF 2 NEW DITERPENE GLYCOSIDES FROM NICOTIANA-TABACUM

Two new diterpene glycosides containing 20-hydroxygeranuyllinalool wer e isolated and identified from Nicotiana tabacum. These compounds cons isted of five molecules of glucose and/or rhamnose. The locations of t he aglycone and glycosides in the molecules were determined by 2D-NMR with the HMBC technique. The structures were hydroxygeranyllinalyl-3-O -[alpha-L-rhamnopyranosyl beta-D-glucopyranoside-20-O-[beta-D-glucopyr anosyl (1-->2)]-[alpha-L-rhamnopyranosyl (1-->6)]-beta-D-glucopyranosi de and hydroxygeranyllinalyl-3-O-[alpha-L-rhamnopyranosyl ta-D-glucopy ranoside-20-O-[alpha-L-rhamnopyranosyl (1-->4)]-[alpha-L-rhamnopyranos yl (1-->6)]-beta-D-glucopyranoside.