The mortality of anxiety syndromes between 1972 and 1992 was investiga
ted in a prospective study of a normal population, the 1947 Lundby coh
ort. 121 persons with anxiety according to the Lundby definition (Anx)
, and 74 persons with panic disorder with/without agoraphobia (PD-Ag)
according to the DSM-III-R, all of them developing their first episode
between 1947 and 1972, were analyzed with regard to general mortality
and special cause of death. Sex- and age-specific mortality rates for
these groups were calculated and compared with the corresponding rate
s of the cohort's 1,877 remaining subjects without first episodes of A
nx/PD-Ag. In contrast to the females, the annual rates of general mort
ality in males with Anx/PD-Ag were 1.9/2.2 times higher in the age gro
up 65-84 years, compared with the rates of the non-Anx/PD-Ag groups. T
hey also had an increase in death due to circulatory disorders, most p
ronounced in males with PD-Ag before the age of 65. There were-no suic
ides in ally of the Anx/PD-Ag groups during the observation period.