COMPARISON OF MAGNETIC-RESONANCE-IMAGING AND TRANSVAGINAL ULTRASONOGRAPHY WITH HYSTEROSALPINGOGRAPHY IN THE EVALUATION OF WOMEN EXPOSED TO DIETHYLSTILBESTROL

OBJECTIVE: To compare the ability of magnetic resonance imaging (MRI) and transvaginal ultrasound (TV-US) with that of hysterosalpingography (HSG) in detecting uterine abnormalities caused by in utero diethylst ilbestrol (DES) exposure. STUDY DESIGN: The study teas a prospective M RI and TV-US blind comparison of DES-exposed and nonexposed subjects w ho had had previous HSG for infertility evaluation. RESULTS: MRI ident ified uterine constrictions in 60% of patients and T-shaped uteri in 2 5% of DES-exposed patients with HSG-confirmed abnormalities. TV-US did not identify uterine constrictions or T-shaped uteri in DES-exposed p atients. CONCLUSION: HSG must still be considered the preferred method in evaluating DES-related uterine abnormalities. HSG-defined uterine abnormalities associated with in utero DES exposure were variably iden tified by MRI and not at all by TV-US.