HIGH-SPEED SEPARATION OF SUBNANOMOLAR CONCENTRATIONS OF NORADRENALINEAND DOPAMINE USING CAPILLARY ZONE ELECTROPHORESIS WITH LASER-INDUCED FLUORESCENCE DETECTION

Authors
BERT L ROBERT F DENOROY L RENAUD B
Citation
L. Bert et al., HIGH-SPEED SEPARATION OF SUBNANOMOLAR CONCENTRATIONS OF NORADRENALINEAND DOPAMINE USING CAPILLARY ZONE ELECTROPHORESIS WITH LASER-INDUCED FLUORESCENCE DETECTION, Electrophoresis, 17(3), 1996, pp. 523-525
Citations number
21
Categorie Soggetti
Biochemical Research Methods
Journal title
Electrophoresis → ACNP
ISSN journal
01730835
Volume
17
Issue
3
Year of publication
1996
Pages
523 - 525
Database
ISI
SICI code
0173-0835(1996)17:3<523:HSOSCO>2.0.ZU;2-J
Abstract
Capillary zone electrophoresis with laser-induced fluorescence detecti on has been shown to give rapid separations with high resolution and s ensitivity. These advantages are documented for catecholamines analysi s in the present work, which shows that separation of subnanomolar con centrations of dopamine and noradrenaline (detection limits of 8.6 x 1 0(-11) M, corresponding to a detected amount of 143 zeptomoles of each catecholamine) can be performed in 82 s with an efficiency of several million theoretical plates.