90K (MAC-2 BP) IN HUMAN-MILK

Human 90K, also known as Mac-2 binding protein (Mac-2 BP), is a secret ed glycoprotein which is widely expressed, binds to the human macropha ge-associated lectin Mac-2, and may have a role in host defence. We ha ve measured the concentrations of 90K in human breast milk from eight healthy mothers delivering mature healthy infants after full-term preg nancy using a specific immunoenzymatic assay. Maximal 90K concentratio ns were observed on days 2-3 post-partum, and ranged from 13.4 to 79.2 mu g/ml. The concentrations of 90K in the milk had no correlation wit h those in the maternal blood.