The life expectancy of patients with cystic fibrosis (CF) has increase
d considerably during the last decades due to improved therapy; one th
ird of German CF patients has now grown into adulthood. The present pa
per describes the main therapeutic principles: oral antistaphylococcal
treatment, therapy of chronic bronchopulmonary infection with Pseudom
onas aeruginosa using intravenous, inhaled or - in adults - oral antib
iotics, and improved regimens for the treatment of malnutrition. Final
ly, survival data from different CF centres are presented.