MANAGEMENT OF EXPERIMENTAL GLOBE PERFORATION DURING STRABISMUS SURGERY

Background: The incidence of potentially vision-threatening globe perf oration during strabismus surgery is reportedly between less than 1% a nd 12% of cases. Optimal treatment of globe perforation is not known; however, traditionally it has been treated with cryotherapy at the tim e of surgery or observation without treatment. The indirect-ophthalmos cope-directed diode laser may provide a safe and effective alternative treatment. Methods: We perforated the globes of six adult Dutch rabbi ts (12 eyes) and treated four eyes with cryotherapy and four with diod e laser; the remaining four were not treated. Results: Histologic exam ination of the untreated eyes revealed a cellular reaction around the polyglactin suture that formed a non-uniform chorioretinal adhesion. T he cryotherapy eyes had a tenuous chorioretinal adhesion and retinal p igment epithelium (RPE) cells in the vitreous on several sections. The laser-treated eyes had a firm, wide chorioretinal adhesion, with mini mal tissue disruption and no release of RPE cells. No complications oc curred. Conclusion: We conclude that indirect-ophthalmoscope-directed diode laser retinopexy was safe and efficacious for globe perforation during strabismus surgery on rabbits and could be expected to be usefu l in humans.