EMPIRICAL MODELING OF SOLVENT POLARITY SCALES

The new dipolarity/polarizability SPPN (100 solvents) scale has been a nalyzed in terms of polarity (Y) and polarizability (P) contributions [SPPN=0.03+1.36Y+0.98P]. It appears that the polarity predominates. Th is and other equations were tried searching for a prediction of SPPN f rom polarity and polarizability scales. Although the best adjusted r(2 ) values are never higher than 0.98, a list of 122 new SPPN values has been calculated, which can be used in studies of solvent effects. An exchange algorithm program was used to select the most significant (in the sense of information content) amongst the 122 new solvents.