LOCALIZATION OF 15 COSMIDS ON HUMAN CHROMOSOME-22 BY FLUORESCENCE INSITU HYBRIDIZATION

Authors
LEVY N LAMOUR V DANGLOT G SLIM R LIPINSKI M BERNHEIM A
Citation
N. Levy et al., LOCALIZATION OF 15 COSMIDS ON HUMAN CHROMOSOME-22 BY FLUORESCENCE INSITU HYBRIDIZATION, Comptes rendus de l'Academie des sciences. Serie 3, Sciences de la vie, 316(5), 1993, pp. 482-486
Citations number
15
Categorie Soggetti
Multidisciplinary Sciences
Journal title
Comptes rendus de l'Academie des sciences. Serie 3, Sciences de la vie → ACNP
ISSN journal
07644469
Volume
316
Issue
5
Year of publication
1993
Pages
482 - 486
Database
ISI
SICI code
0764-4469(1993)316:5<482:LO1COH>2.0.ZU;2-S
Abstract
Fluorescence in situ hybridization has been used in a cytogenetic anal ysis to map 15 cosmids on human chromosome 22. Thirteen cosmids were l ocalized on the long arm of chromosome 22 (22q) while two other probes displayed a hybridization signal on 22p and the short arm of the acro centric chromosomes of groups D and G. The regional assignment of thes e new chromosome markers will improve the mapping of chromosome 22 ; t hey can be used to detect numerical and structural aberrations of this chromosome involved in numerous pathologies.