USE OF LIPOSOME-ASSOCIATED BUPIVACAINE IN A CANCER PAIN SYNDROME

Authors
LAFONT ND LEGROS FJ BOOGAERTS JG
Citation
Nd. Lafont et al., USE OF LIPOSOME-ASSOCIATED BUPIVACAINE IN A CANCER PAIN SYNDROME, Anaesthesia, 51(6), 1996, pp. 578-579
Citations number
16
Categorie Soggetti
Anesthesiology
Journal title
Anaesthesia → ACNP
ISSN journal
00032409
Volume
51
Issue
6
Year of publication
1996
Pages
578 - 579
Database
ISI
SICI code
0003-2409(1996)51:6<578:UOLBIA>2.0.ZU;2-I
Abstract
Bupivacaine 0.25% encapsulated by multilamellar liposomes was administ ered epidurally to a patient suffering pain associated with lung cance r and the effect compared with a plain bupivacaine solution of the sam e concentration. Complete analgesia was produced for 4h with the plain solution and 11h with the liposomal formulation. No motor blockade or haemodynamic instability was observed with the liposome-associated bu pivacaine.