To localize choroidal lesions demonstrated by indocyanine green (ICG)
angiography, retinal blood vessels must be identified. Since retinal b
lood vessels are seen in early-phase ICG angiography and the choroidal
lesions are best seen on the late-phase images, a technique has been
developed to demonstrate retinal blood vessels in the late phase of th
e ICG angiography study. The technique requires the injection of 0.3 m
g of ICG dye mixed in 3.0 cc of diluent. This injection is given betwe
en 30 and 40 minutes into the ICG angiogram. This technique allows vis
ualization of retinal blood vessels, which can be used as landmarks to
localize choroidal lesions. Additionally, this technique, when combin
ed with newly developed computer software programs, permits the mappin
g and tracing of choroidal lesions of the fundus.