Vk. Parnaik, NUCLEOCYTOPLASMIC TRANSPORT OF PROTEINS AND CONTROL OF CELLULAR FUNCTION, Indian Journal of Biochemistry & Biophysics, 33(3), 1996, pp. 164-167
Nucleocytoplasmic transport of proteins occurs through pores embedded
in the nuclear envelope. Recent studies have defined the cytoplasmic f
actors required for signal-mediated import of nuclear proteins. Consid
erable progress has been made in understanding the mechanism of nuclea
r export of proteins by the identification of specific signal sequence
s needed for export. Regulatory molecules have been shown to adopt nov
el mechanisms To control their entry into the nucleus and thereby regu
late their functions.