TREATMENT OF X-LINKED LYMPHOPROLIFERATIVE DISEASE (DUNCAN DISEASE) WITH HIGH-DOSE METHYLPREDNISOLONE AND ETOPOSIDE (VP-16)

Authors
GURGEY A SAYLI T KARA A KALE G BERKEL I
Citation
A. Gurgey et al., TREATMENT OF X-LINKED LYMPHOPROLIFERATIVE DISEASE (DUNCAN DISEASE) WITH HIGH-DOSE METHYLPREDNISOLONE AND ETOPOSIDE (VP-16), Turkish Journal of Pediatrics, 38(2), 1996, pp. 217-222
Citations number
10
Categorie Soggetti
Pediatrics
Journal title
Turkish Journal of Pediatrics → ACNP
ISSN journal
00414301
Volume
38
Issue
2
Year of publication
1996
Pages
217 - 222
Database
ISI
SICI code
0041-4301(1996)38:2<217:TOXLD(>2.0.ZU;2-8
Abstract
A five-year-old boy in the acute phase of X-linked lymphoproliferative (XLP) syndrome (Duncan disease) with high fever and hepatosplenomegal y was treated successfully with high-dose methylprednisolone and VP-16 for 15 months. He had been alive for four years after diagnosis as of this writing. We recommend high-dose methylprednisolone and VP-16 in patients with XLP who have to wait for a suitable donor before bone ma rrow transplantation.