BACKGROUND: We conducted this animal study to investigate the cardiopu
lmonary effects of carbon dioxide pneumothorax during laparoscopic sur
gery and determine what intervention, if any, is necessary for this ph
enomenon. METHODS: A swine animal model was used (n = 8). Animals were
anesthetized and underwent peritoneal insufflation with carbon dioxid
e, A laceration was created in the left diaphragm, pO(2), pCO(2), oxyg
en saturation, peak inspiratory pressure (PIP), systolic blood presssu
re, and heart rate were measured and subjected to statistical analysis
, RESULTS: Significant changes were noted in the pO(2), O-2 saturation
, pCO(2), and PIP upon creation of the pneumothorax. Trends were also
noted in the heart rate and the systolic blood pressure, The physiolog
ic changes could be corrected by noninvasive means and without termina
ting the procedure, CONCLUSIONS: Carbon dioxide pneumothorax produces
reproducible cardiopulmonary changes in laparoscopic surgery, These ch
anges are easily monitored and the resulting cardiopulmonary changes c
an be treated without invasive means.