THE NOVEL ANTIBACTERIAL PEPTIDE CERATOTOXIN A ALTERS PERMEABILITY OF THE INNER-MEMBRANE AND OUTER-MEMBRANE OF ESCHERICHIA-COLI-K-12

Authors
MARRI L DALLAI R MARCHINI D
Citation
L. Marri et al., THE NOVEL ANTIBACTERIAL PEPTIDE CERATOTOXIN A ALTERS PERMEABILITY OF THE INNER-MEMBRANE AND OUTER-MEMBRANE OF ESCHERICHIA-COLI-K-12, Current microbiology, 33(1), 1996, pp. 40-43
Citations number
22
Categorie Soggetti
Microbiology
Journal title
Current microbiology → ACNP
ISSN journal
03438651
Volume
33
Issue
1
Year of publication
1996
Pages
40 - 43
Database
ISI
SICI code
0343-8651(1996)33:1<40:TNAPCA>2.0.ZU;2-A
Abstract
Ceratotoxins are antibacterial 3-kDa amphiphilic peptides isolated fro m the female reproductive apparatus of the medfly Ceratitis capitata. The antibacterial activity of a chemically synthesized ceratotoxin A ( ctx 4) has been investigated. Ctx A was mainly active against Gram-neg ative organisms, and it had a lytic effect on nongrowing Escherichia c oli K-12. Data showed that ctx A alters both the outer and the inner m embrane of E. coli K-12 cells.