MEASURING MALE REPRODUCTIVE HORMONES FOR OCCUPATIONAL FIELD STUDIES

Citation
Sm. Schrader et al., MEASURING MALE REPRODUCTIVE HORMONES FOR OCCUPATIONAL FIELD STUDIES, Journal of occupational medicine, 35(6), 1993, pp. 574-576
Citations number
5
Categorie Soggetti
Public, Environmental & Occupation Heath
Journal title
Journal of occupational medicine
ISSN journal
00961736 → ACNP
Volume
35
Issue
6
Year of publication
1993
Pages
574 - 576
Database
ISI
SICI code
0096-1736(
Abstract
As part Of our longitudinal study of unexposed workers, we drew blood samples and analyzed the individual endocrine profiles for 45 men. The blood collection was between 8 Am and 8 PM, and three blood samples w ere drawn 20 minutes apart on three occasions during the course of the study (June, October, and February). Serum concentrations of follicle -stimulating hormone, luteinizing hormone, testosterone, and prolactin were determined. A component of variance model was used to estimate v ariability between the 20-minute blood draws. Statistical power analys is using this component showed that three blood draws provide a margin al improvement over a single blood draw in detecting population shifts . Also, if the prospect of three blood draws reduces subject participa tion by 10 to 20%, the increase in power would be negated.