M. Chu et al., SCH-65676 - A NOVEL FUNGAL METABOLITE WITH THE INHIBITORY ACTIVITY AGAINST THE CYTOMEGALOVIRUS PROTEASE, Tetrahedron letters, 37(23), 1996, pp. 3943-3946
A new secondary metabolite, Sch 65676 (1), was isolated from the ferme
ntation broth of a fungal culture. The structure of 1 was elucidated b
ased on comprehensive NMR studies including COSY, NOE and HMBC experim
ents. Compound 1 displays inhibitory activity against the cytomegalovi
rus (CMV) protease. (C) 1996 Elsevier Science Ltd