CYCLIZATION OF A CHIRAL OXAZOLIDINE AS A KEY-STEP FOR THE SYNTHESIS OF FUNCTIONALIZED PIPERIDINES

Authors
AGAMI C COUTY F MATHIEU H
Citation
C. Agami et al., CYCLIZATION OF A CHIRAL OXAZOLIDINE AS A KEY-STEP FOR THE SYNTHESIS OF FUNCTIONALIZED PIPERIDINES, Tetrahedron letters, 37(23), 1996, pp. 4001-4002
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
23
Year of publication
1996
Pages
4001 - 4002
Database
ISI
SICI code
0040-4039(1996)37:23<4001:COACOA>2.0.ZU;2-9
Abstract
Bicyclic oxazolidine 6, a potential precursor for the synthesis of ena ntiopure piperidines and indolizidines, was synthesized from (R)-pheny lglycinol. A stereoselective addition of cyanide anion on this compoun d afforded ultimately (2S,3S)-3-hydroxypipecolic acid 9. (C) 1996 Publ ished by Elsevier Science Ltd