Mc. Velezyanguas et Rp. Warrier, THE EVOLUTION OF CHEMOTHERAPEUTIC-AGENTS FOR THE TREATMENT OF PEDIATRIC MUSCULOSKELETAL MALIGNANCIES, The Orthopedic clinics of North America, 27(3), 1996, pp. 545
The incorporation of antineoplastic agents in the treatment of pediatr
ic musculoskeletal malignancies and their impact in the management and
outcome of patients with these types of malignanices are briefly revi
ewed. The role of chemotherapy in the management of these tumors with
special emphasis on osteosarcoma, Ewing's sarcoma family of tumors, an
d rhab-domyosarcoma and undifferentiated sarcomas is discussed. Also i
ncluded are complications and side effects of the antineoplastic agent
s.