PURPOSE: To examine the safety of pulmonary angiography with low-osmol
ar contrast material and modern angiographic techniques and to analyze
periprocedural complications with respect to potential predictors. PA
TIENTS AND METHODS: A retrospective review was conducted of data from
547 consecutive patients who underwent pulmonary angiography, Minor an
d major complications were analyzed by using several clinical paramete
rs. RESULTS: There were five major (0.9%) and 26 minor complications (
4.8%). Eleven of the 26 minor complications were contrast-induced neph
rotoxicity, There were no periprocedural deaths, Patients with complic
ations had an increased incidence of coexistent pulmonary morbidities
and were of a poorer physical status according to the American Society
of Anesthesiology criteria, Moderate to severe pulmonary hypertension
was correlated with major complications. Age, volume of contrast mate
rial used, and presence of pulmonary embolism were not correlated with
complications. CONCLUSION: Pulmonary angiography is a safe procedure
with an acceptable complication rate, These findings should be conside
red in the selection of an imaging method for the diagnosis of pulmona
ry embolism.