Objective-To assess the current value of necropsy in paediatric cardio
logy and cardiothoracic surgery and determine its potential impact on
clinical practice. Design and setting-Descriptive study of all paediat
ric cardiac deaths occurring over four years in a tertiary referral ce
ntre. Data were obtained from reviewing the hospital files, available
necropsy records and specimens, and audit reports. Patients-Paediatric
patients with congenital or acquired heart disease, who died of a car
diac cause between January 1992 and July 1995. Inclusion criteria were
that the diagnosis of heart disease was made before death, and that p
atients were managed thereafter medically and/or surgically at the ref
erral centre. The value of necropsy was assessed according to its cont
ribution in establishing the cause of death (confirmed, clarified, pre
cise cause of death uncertain) and the anatomy (simple confirmation or
additional information provided). For cases not submitted to necropsy
the clinical information relating to the cause of death was assessed
and the case assigned as cause of death firm, uncertain, or unknown. R
esults-One hundred and six deaths were identified (61 males, age at de
ath: one day to 20 years). Seventy occurred early (a month or less) af
ter surgery and were graded as postoperative deaths, The rest were con
sidered to be either medical or late surgical deaths. Necropsy was per
formed in. 59 (55.6%). The precise cause of death was confirmed in 33
(55.9%), clarified in 22 (37.3%), and uncertain in four (7.8%). Additi
onal information regarding the anatomy was found in eight (13.6%) case
s. In five cases the necropsy detected findings if known before death,
would probably have improved outcome. For the patients dying without
a necropsy, the cause of death remained uncertain in 10 (21.3%) and un
known in seven (14.9%). In 36% of cases, therefore, a firm cause of de
ath that might have been provided by a necropsy was missing. Conclusio
n-In paediatric cardiology necropsy continues to provide clinically re
levant information at a high level. It remains vital for ensuring qual
ity of medical care, in instigating improvements in future management,
and increasing understanding of congenital heart disease. The procedu
re should therefore be sought actively in all cases.