E. Hemminki et J. Merilainen, LONG-TERM EFFECTS OF CESAREAN-SECTIONS - ECTOPIC PREGNANCIES AND PLACENTAL PROBLEMS, American journal of obstetrics and gynecology, 174(5), 1996, pp. 1569-1574
OBJECTIVE: Few studies on the long-term effects of cesarean sections e
xist. The purpose of this study was to investigate the occurrence of t
hree long-term effects, ectopic pregnancy, placenta previa, and abrupt
io placentae, in the subsequent pregnancy. STUDY DESIGN: This retrospe
ctive cohort study was based on two nationwide registers in Finland: t
he birth register and the hospital inpatient register. Women (n = 16,9
38) having had a cesarean section (exposed women) and a matched contro
l group were identified from the birth register. The occurrence and ou
tcome of the first subsequent pregnancy was determined from the 1987 t
o 1993 hospital inpatient register and the first subsequent birth from
the 1987 to 1993 birth register. RESULTS: During the follow-up time i
n the hospital inpatient register, fewer exposed women had a completed
pregnancy. Ectopic pregnancy was more common among the exposed women
than among the controls (risk ratio 1.28). In the first subsequent bir
th abruptio placentae was more common among primiparous (at index the
birth, risk ratios of 3.22 in hospital inpatient register and 2.41 in
birth register) and multiparous women (4.52 in hospital inpatient regi
ster and 3.89 in birth register). Placenta previa was more common amon
g primiparous exposed women than among control women (risk ratio 5.34
in hospital inpatient register and 3.78 in birth register). CONCLUSION
S: Cesarean section is a modest risk factor for ectopic pregnancy and
an important risk factor for placental problems.