CLINICAL-SIGNIFICANCE OF PLACENTA-CONFINED NONMOSAIC TRISOMY-16

Citation
H. Brandenburg et al., CLINICAL-SIGNIFICANCE OF PLACENTA-CONFINED NONMOSAIC TRISOMY-16, American journal of obstetrics and gynecology, 174(5), 1996, pp. 1663-1664
Citations number
3
Categorie Soggetti
Obsetric & Gynecology
ISSN journal
00029378
Volume
174
Issue
5
Year of publication
1996
Pages
1663 - 1664
Database
ISI
SICI code
0002-9378(1996)174:5<1663:COPNT>2.0.ZU;2-T
Abstract
Since the introduction of chorionic villi sampling in 1984 we have obs erved five first-trimester cases of nonmosaic placenta confined trisom y 16. At subsequent follow-up it appeared that all five had an adverse maternal or fetal outcome. In three cases the mother had preeclampsia . Two of the infants were born with multiple congenital abnormalities, including tetralogy of Fallot. All children were growth retarded.