COMPARISON OF ARTERIAL-WALL REACTION AFTER PASSAGE OF THE HYDROLYSER DEVICE VERSUS A THROMBECTOMY BALLOON IN AN ANIMAL-MODEL

Citation
Vg. Vanommen et al., COMPARISON OF ARTERIAL-WALL REACTION AFTER PASSAGE OF THE HYDROLYSER DEVICE VERSUS A THROMBECTOMY BALLOON IN AN ANIMAL-MODEL, Journal of vascular and interventional radiology, 7(3), 1996, pp. 451-454
Citations number
16
Categorie Soggetti
Radiology,Nuclear Medicine & Medical Imaging
ISSN journal
10510443
Volume
7
Issue
3
Year of publication
1996
Pages
451 - 454
Database
ISI
SICI code
1051-0443(1996)7:3<451:COARAP>2.0.ZU;2-L
Abstract
PURPOSE: This study was designed to compare the reaction of the vessel wall after application of the Hydrolyser hydrodynamic thrombectomy de vice to the reaction after use of a balloon thrombectomy catheter. The influence of the vessel inner diameter on vessel wall reaction was ev aluated after passage of the Hydrolyser. MATERIALS AND METHODS: After measurement of the vessel inner diameter with intravascular ultrasound (US), 102 segments of femoral and carotid arteries of goats were trea ted with one of the following four procedures: passage of the intravas cular US catheter alone; passage of the Hydrolyser without or with an activated jet; or passage of an inflated thrombectomy balloon. Histolo gic evaluation was performed after 3 weeks. RESULTS: Intimal thickenin g (more than five cell layers of neointima) 3 weeks after treatment oc curred more frequently after passage of the balloon than after any of the other procedures (P <.001). For vessels with a diameter of 3-4 mm, 4-5 mm, or more than 5 mm, no significant difference in vessel wall r eaction was observed following Hydrolyser passage. CONCLUSION: In this model, passage of the Hydrolyser device resulted in less intimal reac tion compared with the thrombectomy balloon.