PROGRESSIVE RATIO SCHEDULES IN DRUG SELF-ADMINISTRATION STUDIES IN RATS - A METHOD TO EVALUATE REINFORCING EFFICACY

Authors
RICHARDSON NR ROBERTS DCS
Citation
Nr. Richardson et Dcs. Roberts, PROGRESSIVE RATIO SCHEDULES IN DRUG SELF-ADMINISTRATION STUDIES IN RATS - A METHOD TO EVALUATE REINFORCING EFFICACY, Journal of neuroscience methods, 66(1), 1996, pp. 1-11
Citations number
71
Categorie Soggetti
Neurosciences
Journal title
Journal of neuroscience methods → ACNP
ISSN journal
01650270
Volume
66
Issue
1
Year of publication
1996
Pages
1 - 11
Database
ISI
SICI code
0165-0270(1996)66:1<1:PRSIDS>2.0.ZU;2-M
Abstract
Drug self-administration studies have recently employed progressive ra tio (PR) schedules to examine psychostimulant and opiate reinforcement . This review addresses the technical, statistical, and theoretical is sues related to the use of the PR schedule in self-administration stud ies in rats. Session parameters adopted for use in our laboratory and the considerations relevant to them are described. The strengths and w eaknesses of the PR schedule are also discussed.