U. Klaning et al., INCREASED OCCURRENCE OF SCHIZOPHRENIA AND OTHER PSYCHIATRIC ILLNESSESAMONG TWINS, British Journal of Psychiatry, 168(6), 1996, pp. 688-692
Background. We wished to establish whether the occurrence of schizophr
enia among twins is the same as among the general population. Method.
Through record linkage between the New Danish Twin Register and the Da
nish Psychiatric Case Register, the twins who have ever received a dia
gnosis of schizophrenia were identified. Through indirect standardisat
ion for age, sex and dates of admission, the rate of first admission w
ith diagnosis schizophrenia among twins is compared to the same rate i
n the general population. Results. A 28% increase in the rate of first
admissions for schizophrenia in twins compared to the general populat
ion was found. This is statistically significant and does not seem to
be caused by any known methodological problems. Twins also had an incr
eased first-admission rate of any psychiatric disorders. Conclusion. T
his increased risk does not seem to be explained by known methodologic
al problems, but does differ from earlier studies.