Epilepsy is a chronic condition whose diagnosis rests on clinical and
electroencephalographic criteria. Computed tomography or magnetic reso
nance imaging demonstrates a cause in 25% of cases. An international c
lassification has been developed that is useful for evaluating the pro
gnosis, the course, and the effect of treatments. Although the pathoph
ysiology of epilepsy has not yet been elucidated, it is hoped that rec
ently-developed functional imaging and genetic techniques will shed ne
w light on this problem. Although neuropsychologic studies can be of u
se for localizing the epileptic focus, few age-specific reference valu
es have been reported. Laboratory tests are indicated when occasional
seizures or metabolic disorders are suspected, as well as in epileptic
children with worsening seizures or possible side effects of drugs.