NEPHROGENIC ADENOMA OF THE BLADDER IN RENAL-TRANSPLANT RECIPIENTS - AREPORT OF 9 CASES WITH ASSESSMENT OF DEOXYRIBONUCLEIC-ACID PLOIDY ANDLONG-TERM FOLLOW-UP

Purpose: We evaluated the outcome of nephrogenic adenoma, a benign tum or rarely encountered in renal transplant recipients. Materials and Me thods: Between 1985 and 1993, 9 renal transplant recipients with a nep hrogenic bladder adenoma removed by endoscopic resection were followed for 24 to 88 months (mean 40). Tumor deoxyribonucleic acid ploidy was assessed by flow cytometry at diagnosis and/or relapse. Results: The relapse rate was 88%. The tumors were diploid and of low proliferating potential, and showed no malignant transformation. Conclusions: Our s tudy confirms the lack of premalignant potential of nephrogenic adenom as. However, since-transplant recipients might be at increased risk fo r bladder cancer, they should be followed closely.