HEMOLYTIC-DISEASE OF THE NEWBORN DUE TO ANTI-K ANTIBODIES

We describe a case of intrauterine foetal death at 32 weeks gestation with signs of hydrops foetalis without erythroblastosis. The hydrops f oetalis appeared to be caused by blood group incompatibility. Irregula r antibodies of anti-g specificity were found in the serum of the moth er, while the father was positive for the K-antigen. The antibody depe ndent cell-mediated cytotoxicity (ADCC) test with serum of the mother was positive. This case shows the characteristics of haemolytic diseas e of the newborn by anti-K. Moreover, it underlines the necessity of b oth adequate follow-up of individual cases, and screening for irregula r antibodies in all pregnancies as well as central registration of scr eening results.