Reexpansion pulmonary edema is a rare complication attending the rapid
reexpansion of a chronically collapsed lung, such as occurs after eva
cuation of a large amount of air or fluid from the pleural space. The
condition usually appears unexpectedly and dramatically-immediately or
within 1 h in 64% of patients and within 24 h in the remainder. The c
linical manifestations are varied; they range from roentgenographic fi
ndings alone in asymptomatic patients to severe cardiorespiratory insu
fficiency. The radiographic evidence of reexpansion pulmonary edema is
a unilateral alveolar filling pattern, seen within a few hours of ree
xpansion of the lung. The edema may progress for 24-48 h and persist f
or 4-5 days, Human data on the pathophysiology of reexpansion pulmonar
y edema derive from small series of patients. case reports, and review
s of the literature. In the other hand, a larger body of ?ata exists o
n experimental reexpansion pulmonary edema in cats, monkeys, rabbits,
sheep, and goats. This review examines the clinical and experimental e
vidence For reexpansion pulmonary edema. In addition, we detail the hi
storical background, clinical setting, treatment, and outcome of reexp
ansion pulmonary edema.