PRODUCTION OF PROTEOLYTIC-ENZYMES BY SOLID-STATE FERMENTATION - AN OVERVIEW

Solid state cultivation systems are in many ways advantageous over sub merged fermentation systems for protease production. This method of fe rmentation can use waste or spent substrates, such as wheat bran and r ice bran for protease production and thus it gains importance from the economic viewpoint over submerged fermentation methods. In addition, solid state fermentation (SSFs), have advantages for low technology ap plications, such as the simplicity of the techniques and the low moist ure content, which can prevent bacterial contamination during fermenta tion. Proteases produced by SSF have been used in food; detergent addi tives, fermentations, End as depilatory agents in the leather industry .