Splenectomy is often performed in patients with malignant disease or t
rauma who are at a high risk of complications. In the long term, it in
creases the risk of infection by encapsulated bacteria. An audit was p
erformed to determine the reasons for splenectomy in a district genera
l hospital, to review the results and complications of surgery, and to
see how often the patients were prescribed antibacterial prophylaxis,
Twenty-eight patients underwent splenectomy in 3 years. The indicatio
n was haematological disease in 13 and trauma in four. In the remainin
g nine the spleen was removed either as part of a radical gastrectomy
or during some other abdominal procedure, Six of the 28 patients had d
ied, one within 30 days from disseminated intravascular coagulopathy f
ollowing an emergency gastrectomy and splenectomy for haematemesis, tw
o from progressive haematological malignant disease, two from nonhaema
tological malignancy, and one from bronchopneumonia. Of the nine patie
nts (32%) with complications, three required a further laparotomy, Mos
t patients had been prescribed pneumococcal vaccine (85%) and prophyla
ctic antibiotics (93%).