DETERMINATION OF MINOR AND TRACE-ELEMENTS IN URINE REFERENCE SAMPLE BY A COMBINED SYSTEM OF INDUCTIVELY-COUPLED PLASMA-MASS SPECTROMETRY AND INDUCTIVELY-COUPLED PLASMA-ATOMIC EMISSION-SPECTROMETRY

Simultaneous multielement determination of minor and trace elements in the urine reference sample by an ICP-MS/AES combined system is descri bed. The biological reference sample of NIST SRM 2670 Freeze-dried Hum an Urine (elevated) was used for analysis. The sample preparation was kept to a minimum: the urine sample was diluted 25-fold with 0.1 M nit ric acid, in which Ge, In and Tl were added as the internal standard e lements. Eighteen elements at the mu g/ml-ng/ml levels were simultaneo usly determined by the present combined system. In addition, the prese nt combined system was also applied to the correction of polyatomic in terference in the determination of chromium in SRM 2670, where interfe rence with Cr-52 due to (ArC)-Ar-40-C-12 was corrected by estimating t he correction factor of (ArC)-Ar-40-C-12 from correlation between the ion count of (ArC)-Ar-40-C-12 and the emission intensity of carbon in the sample.