Aj. Mendez et al., AUTOMATIC DETECTION OF BREAST BORDER AND NIPPLE IN DIGITAL MAMMOGRAMS, Computer methods and programs in biomedicine, 49(3), 1996, pp. 253-262
Advances in the area of computerized image analysis applied to mammogr
aphy may have very important practical applications in automatically d
etecting asymmetries (masses, architectural distortions, etc.) between
the two breasts. We have developed a fully automatic technique to det
ect the breast border and the nipple, this being a necessary prerequis
ite for further image analysis. To detect the breast border, an algori
thm that computes the gradient of gray levels was applied. To detect t
he nipple, three algorithms were compared (maximum height of the breas
t border, maximum gradient, and maximum second derivative of the gray
levels across the median-top section of the breast). A combined method
was also designed. The algorithms were tested on 156 digitized mammog
rams. The breast segmentation results were evaluated by two expert rad
iologists and one physicist. In 89% of the mammograms, the computed bo
rder was in close agreement with the radiologist's estimated border. S
egmentation results were acceptable to be used in computer-aided diagn
ostic schemes. The mean distance between the position of the nipple in
dicated by two radiologists by consensus and the position calculated b
y the computer was 6 mm.